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Pushpawati Singhania Hospital & Research Institute

Pushpawati Singhania Hospital & Research Institute

Press Enclave Marg, Sheikh Sarai II, Near Saket Court, New Delhi - 110017.

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Pushpawati Singhania Hospital & Research Institute

Endovascular Coiling
Endovascular Coiling

Endovascular Coiling (also known as Endovascular Embolization) is a minimally invasive procedure used to treat a brain aneurysm—a weak, bulging spot in an artery wall. Instead of performing traditional open surgery (clipping), the surgeon reaches the brain through the network of blood vessels to "pack" the aneurysm with platinum coils, effectively sealing it off from blood flow and preventing a life-threatening rupture.

  • Unruptured Aneurysms: Found incidentally during scans, these are treated to prevent a future "worst headache of your life" subarachnoid hemorrhage.

  • Ruptured Aneurysms: An emergency intervention to stop further bleeding and stabilize a patient who has suffered a brain bleed.

  • Surgical Risk Factors: When the aneurysm is located in a deep or difficult-to-reach area of the brain where open skull surgery would be too dangerous.

  • Patient Age and Health: Often preferred for older patients or those with medical conditions that make recovery from major open surgery difficult.

  • Specific Anatomy: Aneurysms with a narrow "neck" are ideal candidates for coiling, as the coils are more likely to stay securely inside the bulge.

  • Simple Coiling: Filling the aneurysm with soft platinum coils until blood can no longer enter.

  • Balloon-Assisted Coiling: A temporary balloon is inflated in the main artery to hold coils in place while they are being packed into a wide-necked aneurysm.

  • Stent-Assisted Coiling: A permanent mesh stent is placed across the neck of the aneurysm to act as a scaffold, preventing coils from falling back into the main bloodstream.

  • Flow Diversion: A specialized, high-density stent is placed in the main artery to redirect blood flow away from the aneurysm entirely, causing it to shrink over time without necessarily filling it with coils.

  • Liquid Embolics: In rare cases, a medical "glue" or liquid polymer is used instead of or alongside coils to seal the space.

  • Vascular Access: The surgeon makes a tiny incision in the groin (femoral artery) or wrist (radial artery) and inserts a sheath.

  • Catheter Navigation: A long, thin guide catheter is threaded through the body's main arteries up into the carotid or vertebral arteries in the neck.

  • Microcatheter Placement: Using real-time X-ray guidance (fluoroscopy), a much thinner microcatheter is maneuvered into the brain and directly into the opening of the aneurysm.

  • Coil Deployment: Soft platinum wires (coils) are pushed through the microcatheter. Once they enter the aneurysm, they curl into a mesh ball, filling the space.

  • Induced Thrombosis: The coils disrupt the blood flow, causing the blood inside the aneurysm to clot (thrombose), which creates a solid seal.

  • Final Angiogram: The surgeon performs a final dye test to confirm that blood is flowing normally through the healthy brain arteries and is no longer entering the aneurysm.

  • Digital Subtraction Angiography (DSA): A specialized "map" of the brain's blood vessels is created to measure the aneurysm’s dimensions precisely.

  • Blood Thinner Regimen: For unruptured cases, patients start antiplatelet medications (like aspirin or clopidogrel) days in advance to prevent clots during the procedure.

  • Fasting (NPO): No food or drink for 8–12 hours prior, as the procedure is performed under general anesthesia to ensure total immobility.

  • Kidney Function Check: Blood tests are performed to ensure the kidneys can safely filter the contrast dye used during the X-ray imaging.

  • CT Angiogram (CTA) or MRA: Non-invasive scans used to detect the presence and approximate size of the aneurysm.

  • Digital Subtraction Angiogram (DSA): The gold standard test to see the 3D architecture of the aneurysm neck and its relationship to nearby branches.

  • Platelet Function Test: To ensure that blood-thinning medications are working at the correct level to prevent procedural strokes.

  • Electrocardiogram (EKG): Routine heart monitoring to ensure the patient is fit for general anesthesia.

  • Unruptured Recovery: Most patients stay 1 to 2 days for observation and can return to normal activities within 1 to 2 weeks.

  • Ruptured Recovery: Requires a lengthy stay (14–21 days) in a Neuro-ICU to manage complications like vasospasm (artery tightening).

  • Immediate Post-Op: Patients must lie flat for about 6 hours to ensure the artery access site in the groin or wrist heals properly without bleeding.

  • Medication Adherence: If a stent was used, taking dual blood thinners is mandatory for 6–12 months to keep the stent from clogging.

  • Long-Term Monitoring: Because coils can "compact" or settle, follow-up MRA or angiography scans are required at 6 and 12 months, and periodically thereafter.

  • No Craniotomy: Eliminates the need to open the skull, resulting in significantly less physical trauma and a faster recovery.

  • Reduced Pain: Most patients experience only minor discomfort at the incision site rather than the headaches associated with open brain surgery.

  • Access to Deep Arteries: Allows surgeons to treat aneurysms that are located in areas of the brain that would be impossible or highly dangerous to reach with a scalpel.

  • Proven Efficacy: For many patients, coiling offers a safety profile and success rate comparable to or better than traditional surgical clipping.

Stent-Assisted Coiling
Stent-Assisted Coiling

Stent-Assisted Coiling is an advanced endovascular procedure used to treat wide-necked brain aneurysms that cannot be safely packed with coils alone. In these cases, the opening of the aneurysm is too broad to hold coils in place; the stent acts as a "scaffold" or fence, keeping the coils securely inside the bulge while ensuring the main artery remains open for blood flow.

  • Wide-Necked Aneurysms: Aneurysms where the "neck" (opening) is wider than 4mm or the dome-to-neck ratio is less than 2.

  • Complex Aneurysm Shapes: Irregularly shaped bulges that would otherwise allow coils to "prolapse" or fall back into the parent artery.

  • Recurrent Aneurysms: Cases where previous coiling has settled or compacted, requiring a stent to provide a more permanent seal.

  • Unstable Aneurysms: When the structural integrity of the artery wall needs reinforcement alongside the coiling process.

  • Fusiform Aneurysms: Spindle-shaped bulges that involve a segment of the artery rather than a simple "berry" shape.

  • Jailing Technique: A microcatheter is positioned inside the aneurysm before the stent is deployed. Once the stent is opened, it "jails" the catheter against the wall, allowing the surgeon to pack coils through the mesh.

  • Trans-Stent Technique: The stent is deployed first, and the surgeon then maneuvers a microcatheter through the tiny holes in the stent mesh to reach the aneurysm.

  • Y-Stenting: For aneurysms located at a "fork" in the artery, two stents are placed in a Y-configuration to protect both branching vessels.

  • Self-Expanding Stents: High-tech mesh tubes that automatically expand to the size of the artery when released from the catheter.

  • Balloon-Assisted Stenting: Using a temporary balloon to help position or expand the stent in complex vascular pathways.

  • Vascular Navigation: Using fluoroscopy (real-time X-ray), a guide catheter is threaded from the groin or wrist up to the target artery in the brain.

  • Stent Deployment: The surgeon carefully positions and releases the cylindrical mesh stent across the neck of the aneurysm.

  • Coiling the "Bulge": Through a microcatheter, tiny platinum coils are pushed into the aneurysm. The stent mesh acts as a permanent barrier, preventing any part of the coils from entering the main bloodstream.

  • Flow Disruption: The presence of the stent across the neck helps slow down the blood entering the aneurysm, which aids in the clotting (thrombosis) process.

  • Occlusion Confirmation: Contrast dye is injected to verify that the aneurysm is completely blocked and that the parent artery remains perfectly clear.

  • Incision Closure: The access site in the groin or wrist is closed with a pressure device or a small collagen "plug."

  • Dual Antiplatelet Therapy (DAPT): This is the most critical phase; patients must take Aspirin and Clopidogrel (Plavix) for at least 5–7 days before the procedure to prevent the body from treating the metal stent as a foreign object and forming a clot.

  • 3D Angiography: A high-resolution scan to measure the exact diameter of the parent artery to ensure the stent is sized perfectly.

  • Fasting (NPO): No food or drink for 8–12 hours prior to general anesthesia.

  • Kidney Function Assessment: Ensuring the patient can safely process the contrast dye used for the X-ray mapping.

  • Platelet Function Test (VerifyNow): A blood test to confirm the antiplatelet medications have effectively thinned the blood to the "therapeutic window" for a stent.

  • Digital Subtraction Angiography (DSA): The gold standard for mapping the complex 3D relationship between the aneurysm and nearby arterial branches.

  • CT or MRI Scan: To rule out any recent bleeding or other neurological conditions that might affect the surgical approach.

  • Physical Neurological Baseline: A detailed exam of motor and sensory function to serve as a comparison for post-operative monitoring.

  • Most patients spend 1 to 2 days in a Neuro-ICU for monitoring (unruptured) or 2 to 3 weeks if the aneurysm had previously bled.

  • Strict Medication Adherence: This is life-or-death; missing a single dose of blood thinners in the first 6–12 months can cause the stent to clog, leading to a stroke.

  • Over 6–12 months, the natural lining of the artery grows over the stent (endothelialization), making it a permanent, integrated part of the vessel wall.

  • Patients must follow a strict imaging schedule (MRA or Angiography) at 6, 12, and 24 months to ensure the stent remains open and the aneurysm closed.

  • Normal activity can typically be resumed in 1–2 weeks, though heavy lifting is restricted for the first few days while the incision site heals.

  • Allows for the safe and effective treatment of wide-necked aneurysms that were previously considered "uncoilable."

  • Provides a significantly lower recurrence rate compared to coiling alone, as the stent provides a more robust seal.

  • Offers a minimally invasive alternative to open skull surgery for complex or deep-seated brain aneurysms.

  • The presence of the stent can actually help remodel the artery wall, promoting long-term vascular health.

Balloon-Assisted Coiling
Balloon-Assisted Coiling

Balloon-Assisted Coiling (BAC), also known as the remodeling technique, is a minimally invasive endovascular procedure used to treat brain aneurysms, particularly those with a wide neck or complex shape. It utilizes a temporary balloon to provide a protective barrier while platinum coils are packed into the aneurysm, ensuring the main artery remains clear.

  • Wide-Neck Aneurysms: Aneurysms where the opening is too wide to hold coils on their own (dome-to-neck ratio < 2), preventing them from falling into the bloodstream.

  • Acute Rupture: Often the preferred choice for recently ruptured aneurysms because, unlike stents, it does not require long-term dual antiplatelet therapy, which is dangerous during an active brain bleed.

  • Bifurcation Aneurysms: Useful for aneurysms located where blood vessels branch off, as the balloon helps keep those vital side branches open during the coiling process.

  • Emergency Salvage: When a sudden rupture occurs during a standard coiling procedure, the balloon can be instantly inflated to stop the bleeding.

  • Avoidance of Permanent Hardware: Ideal for patients who cannot tolerate or do not want a permanent metal stent left inside their artery.

  • Standard Remodeling: A single balloon is used to cover the neck of the aneurysm while a second microcatheter delivers the coils.

  • Double-Balloon Technique: Used for extremely complex or wide-base aneurysms, involving two balloons to protect multiple branching vessels simultaneously.

  • Dual-Lumen Ballooning: Utilizing a specialized catheter that can both inflate a balloon and deliver coils through the same device.

  • Temporary Stenting Effect: The balloon is used to "mold" the coil mass into a specific shape that conforms to the aneurysm wall before the balloon is removed.

  • Vascular Navigation: A catheter is inserted, usually through the femoral artery (groin) or radial artery (wrist), and guided to the brain using real-time X-ray imaging (fluoroscopy).

  • Balloon Placement: A specialized balloon microcatheter is positioned in the main artery, directly across the opening (neck) of the aneurysm.

  • Inflation and "Remodeling": The balloon is temporarily inflated with a mixture of saline and contrast dye to create a temporary wall across the aneurysm's neck.

  • Coil Packing: While the balloon is inflated, soft platinum coils are packed into the aneurysm sac. The balloon prevents the coils from protruding into the main artery.

  • Stability Verification: The balloon is periodically deflated to check if the coils remain stable and in place. If they shift, the balloon is reinflated for further packing.

  • Catheter Removal: Once the aneurysm is densely filled and the coils are stable without support, the balloon is deflated and all catheters are removed. No hardware is left in the artery.

  • Diagnostic mapping via Digital Subtraction Angiography (DSA) to determine the exact width of the aneurysm neck.

  • Fasting (NPO) for 8–12 hours prior to the procedure.

  • Administration of heparin (a short-term blood thinner) during the procedure to prevent clots from forming while the balloon is inflated.

  • Baseline neurological assessment to monitor the patient's speech, motor, and sensory functions before and after the surgery.

  • Digital Subtraction Angiography (DSA): The gold standard for measuring the "dome-to-neck" ratio to decide if a balloon is necessary.

  • CT or MRI Scan: To assess the brain for any signs of recent hemorrhage or structural abnormalities.

  • Kidney Function Tests: To ensure the patient's kidneys can safely filter the contrast dye used during the X-ray process.

  • Blood Coagulation Profile: Checking the patient's natural clotting ability before introducing surgical blood thinners.

  • Hospital Stay: Patients are typically monitored for 1 to 2 days for unruptured aneurysms. For ruptured cases, the stay extends to 2 to 3 weeks in a Neuro-ICU.

  • Immediate Post-Op: Strict bed rest is required for 6 hours to prevent bleeding at the catheter insertion site (groin or wrist).

  • Medication: Most patients only require short-term aspirin (2–4 weeks), which is a significant benefit over the months of intense blood thinners required for stents.

  • Activity: Most patients return to normal light activities within 1 to 3 weeks.

  • Follow-up: Mandatory MRA or Angiography scans are performed at 6 and 12 months to ensure the coils haven't settled and the aneurysm remains sealed.

  • No Permanent Implant: Unlike stent-assisted coiling, no metal is left in the main artery, reducing the long-term risk of blood clots or "clogging" (restenosis).

  • Superior Safety in Ruptures: Allows for the treatment of wide-necked aneurysms without the high risk of bleeding complications associated with long-term blood thinners.

  • Immediate Hemorrhage Control: Provides a "safety net" that can immediately stop internal bleeding if the aneurysm ruptures during the procedure.

  • Improved Packing Density: Allows the surgeon to pack more coils into the aneurysm than would be possible without the balloon's support, potentially reducing recurrence.

Carotid Artery Stenting (Stroke Prevention)
Carotid Artery Stenting (Stroke Prevention)

Carotid Artery Stenting (CAS) is a minimally invasive procedure used to open a narrowed carotid artery—the primary blood vessel in the neck that supplies the brain. By using a metal mesh stent to widen the artery, this procedure restores healthy blood flow and significantly reduces the risk of a future stroke. It is often a preferred alternative to open surgery (endarterectomy) for patients with complex anatomy or high-risk medical conditions.

  • Significant Stenosis: Blockage of more than 70% in patients without symptoms, or more than 50% in those with a history of mini-strokes (TIAs).

  • High Surgical Risk: Patients with severe heart or lung disease who may not tolerate the stress of traditional open neck surgery.

  • Difficult Anatomy: When the blockage is located too high or too low in the neck for a surgeon to reach safely with an incision.

  • Restenosis: For patients whose artery has narrowed again after a previous carotid endarterectomy.

  • Radiation-Induced Stenosis: When the narrowing is a result of prior radiation therapy to the neck, making the tissue difficult to operate on traditionally.

  • Vascular Access: A small puncture is made in the femoral artery (groin) or radial artery (wrist) to serve as the entry point for the catheters.

  • Embolic Protection Device (EPD): A tiny filter, shaped like an umbrella, is positioned past the blockage. This "safety net" catches any loose plaque fragments before they can travel to the brain.

  • Predilation (Angioplasty): A small balloon is guided to the site of the narrowing and inflated to prepare the area for the stent.

  • Stent Deployment: A self-expanding metal mesh tube is released across the blockage. It acts as a permanent scaffold, pressing the plaque against the artery walls to keep the vessel open.

  • Post-Dilation: The surgeon may inflate a balloon inside the newly placed stent to ensure it is fully expanded and snug against the artery wall.

  • Filter Removal: Once the stent is secure, the protection filter—along with any captured debris—is folded and removed from the body.

  • Diagnostic Imaging: Confirmation of the blockage via Carotid Ultrasound, CT Angiogram (CTA), or MR Angiogram (MRA).

  • Dual Antiplatelet Therapy (DAPT): Taking Aspirin and Clopidogrel (Plavix) for 3–5 days prior is mandatory to prevent blood clots from forming on the new stent.

  • Fasting (NPO): No food or drink for 8–12 hours before the procedure.

  • Neurological Baseline: A thorough exam of speech, vision, and motor skills is conducted so the team can monitor for changes during the surgery.

  • Carotid Duplex Ultrasound: A non-invasive test using sound waves to measure the speed of blood flow and the degree of narrowing.

  • CT Angiogram (CTA): Provides a detailed 3D view of the calcium and plaque buildup to help the surgeon select the correct stent size.

  • Electrocardiogram (EKG): To ensure the heart is stable, as manipulating the carotid artery can sometimes affect heart rate.

  • Blood Panels: Routine screens to check kidney function (for processing contrast dye) and blood clotting levels.

  • Hospital Stay: Typically 24 hours for close monitoring of blood pressure and neurological status.

  • Immediate Recovery: Patients must remain on bed rest for about 6 hours post-op to ensure the access site in the groin or wrist heals without bleeding.

  • Medication Adherence: This is the most critical step; missing blood thinners in the first 3 to 6 months can cause the stent to clog (stent thrombosis). Lifetime aspirin is usually required.

  • Activity: Heavy lifting and strenuous exercise are restricted for 1 week, though most patients return to normal light activities within a few days.

  • Follow-up Schedule: Ultrasound scans are mandatory at 1 month, 6 months, and then annually to ensure the artery remains open.

  • Minimally Invasive: Avoids a large incision in the neck, reducing the risk of local nerve damage and scarring.

  • Faster Recovery: Most patients return to their normal routine much sooner than those undergoing open surgery.

  • Real-time Monitoring: Since it is usually performed under local anesthesia, the medical team can communicate with the patient throughout the procedure to ensure brain function remains perfect.

  • Effective Stroke Prevention: Long-term studies show that CAS is highly effective at keeping the carotid artery open and preventing future strokes.

Intracranial Artery Stenting
Intracranial Artery Stenting

Intracranial Artery Stenting (IAS) is a minimally invasive procedure used to treat severe narrowing (stenosis) of the arteries located deep inside the brain. By placing a tiny metal mesh tube (stent) to prop open the vessel, the procedure restores critical blood flow and serves as a vital intervention for preventing major ischemic strokes in patients who have not responded to medication alone.

  • High-Grade Stenosis: Blockage of the brain's internal arteries exceeding 70%, particularly when the narrowing is severe enough to limit blood flow.

  • Failed Medical Therapy: Patients who continue to suffer from strokes or mini-strokes (TIAs) despite taking maximum doses of blood thinners and cholesterol-lowering statins.

  • Recurrent TIAs: Frequent "warning strokes" that indicate a specific area of the brain is consistently being starved of oxygen.

  • Hypoperfusion: Cases where advanced imaging shows that a significant portion of brain tissue is at risk of dying because the blood pressure behind the blockage is too low.

  • Specific Vascular Anatomy: When the narrowing is located in a major "trunk" artery of the brain where a total blockage would be catastrophic.

  • Balloon-Expandable Stenting: The stent is mounted on a balloon; as the balloon inflates, it simultaneously opens the artery and expands the stent into place.

  • Self-Expanding Stenting: A highly flexible "low-profile" stent is released from a catheter and automatically expands to the shape of the brain artery.

  • Submaximal Angioplasty: Gently widening the artery with a balloon before placing the stent to reduce the risk of tearing the fragile vessel walls.

  • Drug-Eluting Stenting: Using stents coated with specialized medication to prevent the growth of scar tissue inside the vessel (restenosis).

  • Wingspan Stent System: A specific type of self-expanding stent system designed specifically for the unique, twisty environment of the brain's vasculature.

  • Vascular Access: A catheter is inserted through the femoral artery (groin) or radial artery (wrist) and navigated through the body's main vessels up into the skull.

  • Micro-Navigation: Using real-time, high-definition X-ray (fluoroscopy), a microcatheter is guided through the fragile and twisty arteries deep within the brain to reach the blockage.

  • Pre-Dilation (Angioplasty): A very small, high-pressure balloon is positioned at the blockage and inflated to carefully widen the narrowed segment.

  • Stent Deployment: The micro-stent (made of nitinol or cobalt-chromium) is deployed across the narrowed area. It acts as a permanent internal scaffold to keep the artery open.

  • Blood Flow Assessment: Contrast dye is injected to ensure the artery is successfully propped open and that blood is reaching the distal (further) parts of the brain.

  • Final Verification: The surgeon confirms the stent is perfectly "apposed" (snug) against the artery wall before removing the delivery catheters.

  • Digital Subtraction Angiography (DSA): The gold standard imaging used to measure the exact length and diameter of the blockage before the procedure.

  • Dual Antiplatelet Therapy (DAPT): Taking Aspirin and Clopidogrel (Plavix) for 5–7 days prior is mandatory to prevent the body from forming clots on the metal stent.

  • Platelet Function Test: A mandatory blood test to verify that the antiplatelet medications have reached the "therapeutic window" needed for safe stenting.

  • Fasting (NPO): No food or drink for 8–12 hours prior to general anesthesia, which is required to keep the patient perfectly still.

  • Perfusion CT or MRI: Advanced scans to map exactly how much brain tissue is currently at risk and if the blood flow is significantly restricted.

  • Digital Subtraction Angiography (DSA): Provides the highest-resolution map of the brain's "plumbing" to plan the navigation route.

  • Kidney Function Screen: Checking the patient's ability to safely filter the contrast dye used during the imaging phases.

  • Neurological Baseline: A comprehensive assessment of motor skills, speech, and vision to serve as a comparison for post-operative monitoring.

  • Hospital Stay: Usually 24 to 48 hours in a Neuro-ICU for intensive blood pressure monitoring; keeping blood pressure stable is critical to prevent brain bleeding.

  • Immediate Recovery: Bed rest is required for about 6 hours post-op to ensure the entry site in the groin or wrist heals properly.

  • Strict Medication Adherence: This is mandatory; missing a single dose of blood thinners in the first 6–12 months can cause the stent to clog, leading to a massive stroke.

  • Activity: Most patients can return to normal light activities within a week, but strenuous exercise should be avoided for 1 to 2 weeks.

  • Follow-up Imaging: Mandatory MRA or CTA scans at 3, 6, and 12 months are required to monitor for "over-healing" or scar tissue growth inside the stent.

  • Direct Stroke Prevention: Significantly reduces the long-term risk of a major stroke in the specific area of the brain supplied by the narrowed artery.

  • Restored Brain Function: Many patients report improvements in "brain fog" or chronic dizziness as healthy blood flow is restored to starved brain tissue.

  • Minimally Invasive: Reaches the deep structures of the brain through the blood vessels, avoiding the need for a major open-skull surgery (craniotomy).

  • Immediate Structural Support: Provides a permanent solution to high-grade blockages that have already proven resistant to the best available medications.

Vertebral Artery Stenting
Vertebral Artery Stenting

Vertebral artery stenting is a minimally invasive endovascular procedure used to open narrowed vertebral arteries, which provide critical blood supply to the brainstem and the back of the brain. It is primarily performed to reduce the risk of a vertebrobasilar stroke in patients who have already experienced symptoms like vertigo or minor strokes despite medical treatment. By placing a small mesh tube within the vessel, the procedure restores healthy blood flow to the brain.

  • Symptomatic Narrowing: If you have 50% or greater narrowing of the vertebral artery and continue to experience TIAs (mini-strokes) or minor strokes.

  • Persistent Vertigo: Recurrent dizziness or balance issues caused by "vertebrobasilar insufficiency" that does not improve with medication.

  • Failed Medical Therapy: For patients who have recurrent neurological symptoms despite taking blood thinners and high-dose cholesterol medications.

  • High-Risk Surgical Anatomy: Because traditional open surgery on these deep arteries is highly complex, stenting is the preferred surgical alternative for most patients.

  • Posterior Circulation Stroke: If a previous stroke has been traced back to a blockage in the vertebral artery system.

  • Anaesthesia: The procedure is performed under local anaesthesia with conscious sedation or general anaesthesia, taking about 1 to 2 hours.

  • Access: A small incision is made in the groin (femoral artery) or the wrist (radial artery) to insert a thin, flexible catheter.

  • Guidance: Using real-time X-ray (fluoroscopy), the specialist guides a wire and catheter through the vascular system to the narrowed section of the vertebral artery.

  • Stent Placement: A small, specialized mesh tube (stent) is guided through the catheter and positioned exactly at the site of the blockage.

  • Expansion: The stent is expanded, pushing against the artery walls to flatten the plaque and keeping the vessel held open to restore full blood flow.

  • Completion: The catheter is removed, and the small access site in the groin or wrist is closed with a pressure device or a small stitch.

[Image showing a catheter-guided stent placement in the neck]

  • Diagnostic Angiography: A detailed mapping of your arteries to determine the exact location and degree of the narrowing.

  • Blood Thinning Protocol: You will likely be started on aspirin and clopidogrel (Plavix) several days before the procedure to prevent clots.

  • Kidney Function Tests: To ensure your kidneys can safely process the contrast dye used during the X-ray guidance.

  • Fasting: Following "nothing by mouth" instructions for 6–8 hours prior to your scheduled procedure.

  • Medication Audit: Reviewing all current supplements and medications, especially any that affect blood clotting.

  • CT Angiogram (CTA) or MRA: High-resolution 3D imaging used to visualize the blood vessels in the neck and brain.

  • Doppler Ultrasound: A non-invasive test to measure the speed and direction of blood flow through the vertebral arteries.

  • Neurological Exam: A baseline assessment of your strength, balance, and coordination.

  • ECG: A routine heart check to confirm cardiovascular stability for the duration of the procedure.

  • Hospital Stay: Most patients stay in the hospital overnight for close neurological observation and are discharged the following day.

  • Antiplatelet Therapy: This is the most critical part of aftercare; you must take Dual Antiplatelet Therapy (DAPT), typically aspirin and clopidogrel, for 1 to 6 months to prevent clots.

  • Activity Restrictions: Avoid heavy lifting and strenuous exercise for about 5 to 7 days to allow the artery access site (groin or wrist) to heal.

  • Long-term Monitoring: Regular Doppler ultrasound or CT scans are performed at 3, 6, and 12 months to ensure the stent remains open and free of new plaque.

  • Lifestyle Management: Continued management of blood pressure and cholesterol is essential to prevent "restenosis" (narrowing again).

  • Minimally Invasive: Avoids the need for large neck incisions, leading to less pain and a significantly faster recovery than open surgery.

  • Stroke Prevention: Successfully opening the artery provides a durable defense against life-threatening strokes in the back of the brain.

  • Immediate Flow Restoration: Patients often experience an immediate improvement in blood supply to the brainstem and cerebellum.

  • High Success in the Neck: Stenting the portion of the artery in the neck (extracranial) is considered very safe with low complication rates.

  • Advanced Imaging Guidance: The use of high-tech fluoroscopy allows for sub-millimeter precision when placing the stent within the vessel.

AVM Embolization
AVM Embolization

AVM (Arteriovenous Malformation) Embolization is a minimally invasive, catheter-based procedure used to block or reduce blood flow to an abnormal tangle of blood vessels. It is most commonly used to treat brain AVMs but can also address malformations in the spine or other parts of the body. By plugging the "feeding" arteries of the malformation, the procedure stabilizes the vascular structure and reduces the risk of life-threatening hemorrhages.

  • Pre-Surgical Preparation: To shrink the AVM and block deep, hard-to-reach feeding vessels, making surgical removal (resection) safer by significantly reducing blood loss.

  • Pre-Radiosurgical Adjunct: To reduce the total volume of the AVM, making it a better candidate for targeted Stereotactic Radiosurgery (SRS).

  • Vascular Steal Syndrome: When the AVM "steals" blood from healthy brain tissue, causing chronic headaches, seizures, or progressive neurological deficits.

  • High Rupture Risk: If diagnostic imaging shows weakened vessel walls (aneurysms) within the AVM that are at high risk of bleeding.

  • Inoperable AVMs: For malformations located in "eloquent" or deep areas of the brain where traditional open surgery is too risky.

  • Access: A thin, flexible tube called a catheter is inserted into a major artery, usually in the groin (femoral) or the wrist (radial). No skull incisions are required.

  • Anesthesia: The procedure is typically performed by a neurointerventional specialist under general anesthesia and lasts between 2 to 3 hours.

  • Guidance: Using real-time X-ray imaging (fluoroscopy) and contrast dye, the surgeon threads the micro-catheter through the vascular system directly to the AVM's feeding vessels.

  • Blocking (Embolization): A specialized "embolic agent" is injected through the catheter to seal the vessels. Common agents include:
    Liquid Glues (Onyx or NBCA): Medical-grade substances that harden quickly to permanently seal the abnormal vessels.
    Microcoils: Tiny platinum or steel coils that trigger the body's natural clotting process.
    Particles: Small medical grains that physically plug the smaller, intricate vessels of the AVM.

  • Completion: Once the desired blood flow reduction is achieved, the catheter is removed, and the access site is closed with a pressure device.

[Image showing the "Onyx" embolic agent filling the AVM nest]

  • Cerebral Angiography: A detailed "road map" of your brain's blood vessels to identify the exact feeders of the AVM.

  • Neurological Baseline: A comprehensive exam to document your current motor skills, speech, and vision before the procedure.

  • Kidney Function Tests: To ensure your body can safely clear the contrast dye used during the imaging process.

  • Fasting: Following "nothing by mouth" instructions for 8 hours prior to your scheduled anesthesia.

  • Medication Audit: You may be asked to stop taking blood thinners several days before the procedure to minimize the risk of bleeding at the access site.

  • CT or MRI Scan: To visualize the relationship between the AVM and the surrounding healthy brain tissue.

  • Functional MRI (fMRI): Occasionally used to map critical areas of the brain (like speech or movement centers) near the AVM.

  • Blood Panels: A routine check of your blood count and coagulation profile to ensure a safe surgical experience.

  • ECG: A standard heart check to confirm you are healthy enough for the administration of anesthesia.

  • Hospital Stay: Most patients stay at least one night for close observation. If the AVM has previously ruptured, a longer stay in a neuro-intensive care unit (ICU) may be required.

  • Immediate Symptoms: It is normal to experience mild headaches, nausea, or temporary fatigue for a few days following the procedure.

  • Activity Restrictions: Avoid heavy lifting and strenuous exercise for about 5 to 7 days to allow the artery access site (groin or wrist) to heal completely.

  • Follow-up Imaging: A repeat angiography is typically performed within 6 to 12 months to check for recanalization (vessels reopening) or new blood flow pathways.

  • Multidisciplinary Care: Embolization is often just one step; you will continue to be monitored by a team including neurosurgeons and radiation oncologists.

  • Minimally Invasive Access: Treating complex brain vascular issues through a tiny puncture in the wrist or groin avoids the need for a craniotomy.

  • Enhanced Surgical Safety: By "turning off" the high-pressure blood flow to the AVM, surgeons can remove the remaining malformation with much higher precision and lower risk.

  • Immediate Pressure Reduction: Successfully blocking feeding vessels reduces the immediate strain on fragile AVM walls, lowering the risk of a sudden hemorrhage.

  • Precision Delivery: Modern micro-catheters can navigate deep into the brain's smallest vessels, allowing for highly targeted treatment of even the most complex malformations.

  • Symptom Resolution: Many patients find that redirected blood flow to healthy brain tissue alleviates chronic seizures and headaches.

Dural AV Fistula Embolization
Dural AV Fistula Embolization

Dural Arteriovenous Fistula (DAVF) Embolization is a specialized endovascular procedure used to close abnormal connections (fistulas) between the dural arteries and the venous system surrounding the brain or spinal cord. Unlike congenital malformations, DAVFs are typically acquired later in life due to factors such as trauma, blood clots (sinus thrombosis), or infections. The procedure uses a catheter-based approach to navigate the vascular system and "plug" the high-pressure leak into the veins.

  • Cortical Venous Reflux: A high-risk condition where blood flows backward into the brain's veins, significantly increasing the risk of a life-threatening hemorrhage or stroke.

  • Pulsatile Tinnitus: A debilitating "whooshing" or rhythmic thumping sound in the ear that matches your heartbeat, caused by high-pressure blood flow near the ear structures.

  • Increased Intracranial Pressure: When the fistula interferes with normal drainage, causing severe headaches, nausea, or progressive vision loss.

  • Neurological Deficits: Sudden or progressive weakness, numbness, or seizures caused by "venous congestion" in the brain or spinal cord.

  • Aggressive Lesion Grading: If diagnostic imaging (Borden or Cognard classification) identifies the fistula as high-grade with a significant risk of bleeding.

  • Access: A thin, flexible catheter is inserted into a blood vessel in the groin or wrist and threaded toward the brain using real-time X-ray guidance (fluoroscopy).

  • Anesthesia: The procedure is typically performed under general anesthesia to ensure the patient remains perfectly still, taking approximately 2 to 4 hours.

  • Transarterial Route: The most common approach, reaching the fistula through the feeding dural arteries (such as the middle meningeal artery).

  • Transvenous Route: An alternative or combined approach accessing the site through the venous sinuses, which is often highly effective for specific high-grade lesions.

  • Embolization: Once the catheter is at the target, "embolic agents" are injected to permanently seal the connection. Common agents include:
    Liquid Embolics (Onyx or PHIL): Non-adhesive liquids that harden upon contact with blood to fill the fistula "nest."
    Microcoils: Small platinum coils that trigger the body's natural clotting process.
    Medical Glue (NBCA): A fast-acting adhesive used to instantly seal high-flow connections.

  • Digital Subtraction Angiography (DSA): The "gold standard" diagnostic test to map the complex architecture of the fistula and its feeding vessels.

  • Neurological Assessment: A detailed baseline exam of your vision, motor function, and cranial nerves.

  • Kidney Function Tests: To ensure your kidneys can safely process the contrast dye used during the X-ray guidance.

  • Fasting: Following "nothing by mouth" instructions for 8 hours prior to the administration of anesthesia.

  • Medication Audit: You may be asked to stop taking blood thinners several days before the procedure to minimize the risk of bleeding at the access site.

  • MRI or CT Angiography: To visualize the relationship between the fistula, the dural sinuses, and the surrounding brain tissue.

  • Formal Hearing Test: Often required for patients presenting with pulsatile tinnitus to establish a baseline.

  • Blood Panels: A routine check of your blood count and clotting factors to ensure a safe endovascular experience.

  • ECG: A standard heart check to confirm cardiovascular stability for the duration of the procedure.

  • Hospital Stay: Patients are typically monitored in the hospital for 1 to 2 days to ensure there are no changes in neurological status.

  • Immediate Symptoms: It is normal to experience mild headaches and soreness at the puncture site (groin or wrist) for 2–3 days.

  • Activity Restrictions: No heavy lifting (over 4.5 kg / 10 lbs) or strenuous exercise for 5 days following the procedure to allow the access site to heal.

  • Follow-up Imaging: A repeat angiography is usually performed at 6 and 12 months to ensure the fistula remains completely closed.

  • Symptom Resolution: Most patients notice an immediate disappearance of pulsatile tinnitus and a gradual reduction in headaches as the venous pressure normalizes.

  • Minimally Invasive: Treating complex brain vascular connections through a tiny puncture in the wrist or groin avoids the risks and recovery time of a craniotomy.

  • High Success Rates: Modern embolic agents allow for complete occlusion of the fistula in 72% to 90% of cases in a single session.

  • Targeted Pressure Relief: By closing the fistula, the procedure immediately stops the dangerous backward flow of blood into the brain's delicate veins.

  • Preserves Normal Flow: Advanced micro-catheters allow specialists to seal the abnormal connection while carefully preserving the healthy blood flow necessary for brain function.

  • Prevents Future Stroke: Definitive closure of high-risk fistulas provides a durable defense against intracranial hemorrhage and long-term neurological damage.

Deep Brain Stimulation (DBS)
Deep Brain Stimulation (DBS)

Deep Brain Stimulation (DBS) is a neurosurgical procedure that uses a "brain pacemaker" to send electrical impulses to specific areas of the brain. As of 2026, it is an established standard of care for movement disorders and is increasingly used for psychiatric conditions when traditional medications fail.

  • Parkinson’s Disease symptoms such as tremors, rigidity, and "off" time that are no longer managed by medication.

  • Essential Tremor causing severe, uncontrollable shaking in the hands and arms.

  • Dystonia involving painful or involuntary muscle contractions.

  • Epilepsy characterized by refractory partial-onset seizures.

  • Treatment-resistant Obsessive-Compulsive Disorder (OCD).

  • Parkinson’s Disease: Significantly reduces tremors and motor fluctuations.

  • Essential Tremor: Suppresses severe shaking to improve daily function.

  • Dystonia: Helps control involuntary muscle movements and postures.

  • Epilepsy: Approved as an adjunctive therapy for difficult-to-treat seizures.

  • Obsessive-Compulsive Disorder (OCD): Used under a humanitarian device exemption for chronic, severe cases.

  • Adaptive DBS (aDBS): Systems that sense real-time brain activity and automatically adjust stimulation levels.

  • Directional Leads: Electrodes that allow surgeons to "steer" current toward targets to minimize side effects.

  • Personalized Programming: Precise digital adjustment of electrical pulses tailored to the patient's brain signals.

  • Sensing Technology: Capability to record brain signals (local field potentials) to monitor disease progression.

  • Improved Battery Life: Advances in battery chemistry providing longer intervals between replacements.

  • Brain Surgery (Stage 1): Fine leads are placed in specific brain targets, often while the patient is awake to test for relief.

  • Testing: Surgeons use microelectrode recording to ensure the leads are in the optimal location.

  • Chest Surgery (Stage 2): The pulse generator (battery) is implanted under the skin near the collarbone.

  • Connection: Extension wires are tunneled under the skin to connect the chest device to the brain leads.

  • Closing: Small incisions are closed with sutures or surgical staples.

  • Hospital Stay: Most patients stay for 1–3 days for observation.

  • Honeymoon Effect: Temporary symptom relief may occur immediately from the surgery itself.

  • Device Activation: Official programming and device "turn-on" typically occurs 2–4 weeks after surgery.

  • Rechargeable Models: Newer 2026 models can last up to 15 years before needing replacement.

  • Non-Rechargeable Models: Standard batteries typically last between 3–5 years.

  • Brain Bleed: There is a 1–3% risk of a brain bleed or stroke during lead placement.

  • Infection: A 3–5% risk of infection exists at the incision sites or around the hardware.

  • Hardware Issues: Potential for lead migration, wire breakage, or skin erosion over the device.

  • Side Effects: Stimulation can sometimes cause temporary speech, balance, or mood changes.

  • Programming Time: It may take several months of adjustments to find the most effective settings.

  • Substantial reduction in the need for daily medications and their associated side effects.

  • Significant improvement in the ability to perform activities of daily living.

  • Continuous, 24-hour symptom control that does not "wear off" like oral medication.

  • Reversible and adjustable technology that can be updated as the condition changes.

  • Enhanced quality of life and independence for patients with chronic movement disorders.

Top Doctors at Pushpawati Singhania Hospital & Research Institute in India

Dr Nitin Kumar Sethi
Dr Nitin Kumar Sethi
Neurologist
Pushpawati Singhania Hospital & Research Institute, New Delhi
27+years experience

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