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Gastrectomy (Stomach Cancer) treatment

Gastrectomy (Stomach Cancer)

  1. Home
  2. Treatment
  3. Gastrectomy (Stomach Cancer)

Stomach Cancer Treatment

Stomach Cancer Treatment, also known as Gastric Cancer Treatment, involves a range of medical and surgical interventions to eliminate malignant growths within the stomach lining. Clinical protocols prioritize the removal of adenocarcinomas while preserving digestive function, utilizing precision therapies to target specific genetic markers and improve long-term outcomes for patients.

When You Should Consider Screening

  • Persistent Indigestion: A lasting burning sensation in the upper abdomen.

  • Early Satiety: Feeling unusually full or bloated after consuming only small meals.

  • Nausea and Vomiting: Chronic episodes, particularly if blood is present.

  • Dysphagia: Difficulty swallowing or a sensation of food being "stuck" in the esophagus.

  • Tarry Stools: Black, sticky stools which may indicate internal gastrointestinal bleeding.

  • Unexplained Fatigue: Persistent weakness often associated with anemia.

Conditions That Require Specialized Care

  • Gastric Adenocarcinomas: Originating in the glandular cells of the stomach mucosa.

  • HER2-Positive Tumors: Stomach cancers that require specific targeted medications.

  • CLDN18.2-Positive Cancers: Identified through modern molecular profiling.

  • H. pylori Infections: Chronic bacterial infections that have led to malignant cellular changes.

  • Genetic Syndromes: Diffuse gastric cancer related to inherited conditions or Lynch syndrome.

How Is Performed

  • Endoscopy: An upper endoscopy is conducted to visualize the stomach lining and obtain tissue biopsies.

  • Staging: Advanced imaging and endoscopic ultrasounds are used to determine the depth of the tumor.

  • Surgical Resection: Intervention is performed to remove part or all of the affected stomach tissue.

  • Perioperative Therapy: Chemotherapy is often administered to shrink the tumor before the primary procedure.

  • Targeted Biology: Biological therapies are introduced to attack specific proteins on the cancer cells.

  • Systematic Immunotherapy: Utilized to enhance the body's natural response to the malignancy.

Types of Stomach Cancer Treatment

  • Partial Gastrectomy: The surgical removal of the specific portion of the stomach containing the tumor and nearby lymph nodes.

  • Total Gastrectomy: A procedure where the entire stomach is removed and the esophagus is connected directly to the small intestine.

  • Targeted Therapy: The use of specialized drugs like Trastuzumab or Zolbetuximab to attack specific cancer cell markers.

  • Immunotherapy: Checkpoint inhibitors that empower the immune system to recognize and destroy gastric cancer cells.

  • Endoscopic Mucosal Resection: A minimally invasive technique used to remove very early-stage tumors during an endoscopy.

  • HIPEC (Heated Chemotherapy): The delivery of heated chemotherapy directly into the abdominal cavity during surgery for advanced cases.

Pre-Procedure Preparation

  • Nutritional Counseling: Consult with a specialized dietitian to manage intake and prepare for digestive changes.

  • Physical Assessment: A comprehensive evaluation to ensure readiness for general anesthesia.

  • Medication Audit: Adhering to specific adjustments as advised by the surgical oncology team.

  • Fasting Protocols: Strict adherence to fasting in the hours leading up to the scheduled procedure.

  • Support Planning: Arranging for assistance during the transition to a modified eating schedule.

Tests Before Stomach Cancer Treatment

  • Upper GI Endoscopy: To provide a direct view of the gastric environment and tumor site.

  • Endoscopic Ultrasound (EUS): To evaluate how far the cancer has invaded the stomach wall.

  • CT and PET Scans: To check for the spread of cells to the liver, lungs, or lymph nodes.

  • Biomarker Testing: HER2 and CLDN18.2 testing to determine the most effective drug therapies.

  • Blood Work: Complete Blood Count (CBC) and iron studies to assess for internal blood loss.

Life After Stomach Cancer Treatment

  • Dietary Adaptation: Adopting a lifestyle of eating small, frequent, and nutrient-dense meals throughout the day.

  • Supplementation: Regular vitamin and mineral support, particularly Vitamin B12, following a gastrectomy.

  • Routine Surveillance: Ongoing monitoring through imaging and endoscopy to ensure continued remission.

  • Weight Management: Consultation with nutritionists to maintain a healthy weight and energy levels.

  • Survivorship Support: Participation in programs to manage the emotional and physical impact of the disease.

Why Specialized Treatment Is Highly Effective

  • Precision Guidelines: Matches therapies with the tumor's specific molecular profile.

  • Perioperative Success: Significantly reduces the risk of cancer recurrence through timed therapy.

  • Minimally Invasive Options: Results in faster recovery and less discomfort for eligible patients.

  • Targeted Strategies: Provides life-prolonging options even for advanced or metastatic conditions.

  • Integrated Care: Maintains high standards of digestive and nutritional health through multidisciplinary teams.

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